(6-methoxy-3-oxo-2,3-dihydro-1H-inden-1-yl)acetic acid

(6-methoxy-3-oxo-2,3-dihydro-1H-inden-1-yl)acetic acid - Names and Identifiers

Name	5-methoxy-1-indanone-3-acetic acid
Synonyms	6-METHOXY-3-OXO-1-INDANACETIC ACID 5-methoxy-1-indanone-3-acetic acid 5-METHOXY-1-INDANONE-3-ACETIC ACID 5-Methoxy-1-oxoindane-3-acetic acid 5-methoxy-4-oxoindan-3-ylacetic acid 5-METHOXY-1-INDANONE-3-ACETIC ACID, TECH . 2,3-dihydro-6-methoxy-3-oxo-1h-indene-1-aceticaci 6-methoxy-3-oxo-2,3-dihydro-1h-indene-1-aceticacid 2,3-Dihydro-6-methoxy-3-oxo-1H-indene-1-acetic acid (6-methoxy-3-oxo-2,3-dihydro-1H-inden-1-yl)acetic acid
CAS	24467-92-3
InChI	InChI=1/C12H12O4/c1-16-8-2-3-9-10(6-8)7(4-11(9)13)5-12(14)15/h2-3,6-7H,4-5H2,1H3,(H,14,15)

(6-methoxy-3-oxo-2,3-dihydro-1H-inden-1-yl)acetic acid - Physico-chemical Properties

Molecular Formula	C12H12O4
Molar Mass	220.22
Density	1.286
Melting Point	139-144 °C (lit.)
Boling Point	429℃
Flash Point	171℃
Solubility	chloroform: soluble5%, clear, yellow-brown
Vapor Presure	4.11E-08mmHg at 25°C
Storage Condition	Room Temprature
Refractive Index	1.569

(6-methoxy-3-oxo-2,3-dihydro-1H-inden-1-yl)acetic acid - Risk and Safety

WGK Germany	3
RTECS	NK8225760

(6-methoxy-3-oxo-2,3-dihydro-1H-inden-1-yl)acetic acid - Introduction

5-methoxy-1-indanone-3-acetic acid is an organic compound with the chemical formula C13H14O4.

Nature:
-Appearance: Colorless to light yellow crystal or powder
-Melting point: about 83-86 degrees Celsius
-Boiling point: about 400 degrees Celsius
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol and dichloromethane
-Typical keto and acidic characteristics

Use:
- 5-methoxy-1-indanone-3-acetic acid is an intermediate of organic synthesis, widely used in the fields of medicine and agrochemical.
-In medicine, it can be used to synthesize anti-inflammatory, analgesic and anti-cancer drugs.
-In agrochemistry, it can be used for synthetic pesticides and herbicides.

Method:
There are many synthesis methods of 5-methoxy-1-indanone-3-acetic acid. The following is a common preparation method:
1. First, methoxy styrene is reacted with methoxy lithium to generate 5-methoxy -1-indanone.
2. 5-methoxy-1-indanone is then reacted with sodium hydroxide/ethyl acetate to produce 5-methoxy-1-indanone-3-acetic acid.

Safety Information:
5-methoxy-1-indanone-3-acetic acid is relatively safe under general conditions of use, but the following matters still need to be paid attention:
-May be irritating to skin and eyes, avoid skin contact and inhalation when in contact.
-Wear appropriate protective equipment, such as chemical gloves and safety glasses.
-During operation and storage, avoid contact with oxidants, strong acids or strong bases.
-If ingested or inhaled, seek medical attention immediately.

Last Update：2024-04-09 21:01:54